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Pharmacology
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Prescription drug shortages force tough treatment decisions
Prescription drug shortages reach all-time high, forcing tough treatment decisions A panel of experts from Johns Hopkins University discusses the current shortage in chemotherapy drugs, antibiotics,
Prescription drug shortages reach all-time high, forcing tough treatment decisions A panel of experts from Johns Hopkins University discusses the current shortage in chemotherapy drugs, antibiotics,
Joining the battle against health care bias
Leo Anthony Celi invites industry to broaden its focus in gathering and analyzing clinical data for every population.
Leo Anthony Celi invites industry to broaden its focus in gathering and analyzing clinical data for every population.
New course offers study of emerging field
The course, designed by Deok-Ho Kim, focuses on microphysiological systems which are used to study human disease, drug development, and precision medicine On a recent Tuesday, biomedical engineering students gathered in Clark Hall to see the fruits of their labor.
The course, designed by Deok-Ho Kim, focuses on microphysiological systems which are used to study human disease, drug development, and precision medicine On a recent Tuesday, biomedical engineering students gathered in Clark Hall to see the fruits of their labor.
As ’deprescribing’ medicines for older adults catches on, poll shows need for patient-provider dialogue
Majority of people over 50 are open to stopping one or more of their medications, but some of those who already did so didn't talk with a health provider first National Poll on Healthy Aging: Views on Medication Deprescribing Among Adults Age 50-80 As the movement toward "deprescribing” medications among older adults grows, a new poll shows strong interest in the idea.
Majority of people over 50 are open to stopping one or more of their medications, but some of those who already did so didn't talk with a health provider first National Poll on Healthy Aging: Views on Medication Deprescribing Among Adults Age 50-80 As the movement toward "deprescribing” medications among older adults grows, a new poll shows strong interest in the idea.
’Alexa, set the alarm for me to take my medication’
Older adults use voice assistant devices more often with training and flyers with instructions to complement their daily routine, according to a new University of Michigan study that looked at long-term usage.
Older adults use voice assistant devices more often with training and flyers with instructions to complement their daily routine, according to a new University of Michigan study that looked at long-term usage.
U-M receives $71M NIH grant to advance clinical, translational science
MICHR to tackle goal of diversifying, improving research to speed therapies for benefit of all patients Traditionally, the timeline for translating research into effective therapies for disease has been long.
MICHR to tackle goal of diversifying, improving research to speed therapies for benefit of all patients Traditionally, the timeline for translating research into effective therapies for disease has been long.
Drug overdose fatalities among older adults have quadrupled in past 20 years
April 4, 2023 The rate of overdose deaths among people age 65 and older quadrupled over the 20-year period starting in 2002, according to a new study co-authored by UCLA Health's Chelsea Shover.
April 4, 2023 The rate of overdose deaths among people age 65 and older quadrupled over the 20-year period starting in 2002, according to a new study co-authored by UCLA Health's Chelsea Shover.
OTC Narcan: A big win for public health
Over-the-counter Narcan: A big win for public health Public health experts from Johns Hopkins share their insights on the FDA's approval of over-the-counter Narcan, which puts the lifesaving medicine
Over-the-counter Narcan: A big win for public health Public health experts from Johns Hopkins share their insights on the FDA's approval of over-the-counter Narcan, which puts the lifesaving medicine
FDA approves OTC naloxone
FACULTY Q&A The Food and Drug Administration has approved a recommendation that naloxone, the opioid overdose reversal drug commonly known as Narcan, be made available over the counter without a prescription.
FACULTY Q&A The Food and Drug Administration has approved a recommendation that naloxone, the opioid overdose reversal drug commonly known as Narcan, be made available over the counter without a prescription.
New funding to protect bats from fungal epidemic hinges on UW-Madison discoveries
University of Wisconsin-Madison pediatrician Bruce Klein is trying to save bats.
University of Wisconsin-Madison pediatrician Bruce Klein is trying to save bats.
Toxic trade-offs
While advances in immunotherapy have dramatically improved cancer survival, unleashing the immune system can lead to a host of adverse-sometimes life-threatening-reactions.
While advances in immunotherapy have dramatically improved cancer survival, unleashing the immune system can lead to a host of adverse-sometimes life-threatening-reactions.
Are demographics getting in the way of pain management?
Imagine that you are in pain. Maybe you stepped off a ladder and hurt your shoulder. The pain isn't intense enough for you to go to the doctor immediately, so you wait. Before you know it, the pain won't let you sleep, and you can't carry your groceries. You finally run to the doctor expecting they'll diagnose the underlying cause of your pain and relieve your symptoms.
Imagine that you are in pain. Maybe you stepped off a ladder and hurt your shoulder. The pain isn't intense enough for you to go to the doctor immediately, so you wait. Before you know it, the pain won't let you sleep, and you can't carry your groceries. You finally run to the doctor expecting they'll diagnose the underlying cause of your pain and relieve your symptoms.
Hopkins COVID-19 data hub ends after three years
Johns Hopkins Coronavirus Resource Center ceased collecting and reporting pandemic data J ohns Hopkins University & Medicine's Coronavirus Resource Center ceased collecting and reporting COVID-19
Johns Hopkins Coronavirus Resource Center ceased collecting and reporting pandemic data J ohns Hopkins University & Medicine's Coronavirus Resource Center ceased collecting and reporting COVID-19
MIT-Takeda Program heads into fourth year with crop of 10 new projects
The program leverages MIT's research expertise and Takeda's industrial know-how for research in artificial intelligence and medicine. Close In 2020, the School of Engineering and Takeda Pharmaceutical Company launched the MIT-Takeda Program, which aims to leverage the experience of both entities to solve problems at the intersection of health care, medicine, and artificial intelligence.
The program leverages MIT's research expertise and Takeda's industrial know-how for research in artificial intelligence and medicine. Close In 2020, the School of Engineering and Takeda Pharmaceutical Company launched the MIT-Takeda Program, which aims to leverage the experience of both entities to solve problems at the intersection of health care, medicine, and artificial intelligence.
LLNL biomedical licensee collaborating with two drug companies to advance treatments for autoimmune diseases
People afflicted with autoimmune diseases may someday receive help through treatments now under development by a Lawrence Livermore National Laboratory (LLNL) licensee and its' collaborations with two major pharmaceutical companies. In late 2017, LLNL licensed a biomedical technology called nanolipoprotein particles (NLPs), which can deliver vaccines and drugs inside the cells in the human body, to Ann Arbor, Michigan-based EVOQ Therapeutics.
People afflicted with autoimmune diseases may someday receive help through treatments now under development by a Lawrence Livermore National Laboratory (LLNL) licensee and its' collaborations with two major pharmaceutical companies. In late 2017, LLNL licensed a biomedical technology called nanolipoprotein particles (NLPs), which can deliver vaccines and drugs inside the cells in the human body, to Ann Arbor, Michigan-based EVOQ Therapeutics.
A new educational program for scientists working on substance use disorder
MIT Open Learning team awarded NIH grant to provide training in biomedical product development, entrepreneurship, and innovation.
MIT Open Learning team awarded NIH grant to provide training in biomedical product development, entrepreneurship, and innovation.
Delivering mRNA Therapeutics to the Pancreas
"We've created technology that delivers to a very important organ." - Kathryn Whitehead When nanoparticles need to go to the pancreas, Kathryn Whitehead can get them there. "We've created technology that delivers to a very important organ," said Whitehead, a professor of chemical engineering and biomedical engineering at Carnegie Mellon University.
"We've created technology that delivers to a very important organ." - Kathryn Whitehead When nanoparticles need to go to the pancreas, Kathryn Whitehead can get them there. "We've created technology that delivers to a very important organ," said Whitehead, a professor of chemical engineering and biomedical engineering at Carnegie Mellon University.
The thorny history of sickle cell anemia
As part of the university's Racism and Repair in the Modern Academy project, Johns Hopkins researchers look inward at the past, present, and future of treatment for this disease.
As part of the university's Racism and Repair in the Modern Academy project, Johns Hopkins researchers look inward at the past, present, and future of treatment for this disease.
Loophole enables FDA approval of unsafe medical devices, Yale study finds
Manufacturers, through a loophole in the law, can use an unsafe medical device as a basis for FDA authorization to bring it to market.
Manufacturers, through a loophole in the law, can use an unsafe medical device as a basis for FDA authorization to bring it to market.
3 Questions: What to expect from respiratory illnesses, including Covid-19, this winter
MIT Medical Director Cecilia Stuopis says that while this is a time to be more vigilant, people should not panic.
MIT Medical Director Cecilia Stuopis says that while this is a time to be more vigilant, people should not panic.
Monash University and Ono Pharmaceutical Announce Collaboration Agreement
An Option and Research Collaboration Agreement has been established between Monash University and Japan-based Ono Pharmaceutical Co. Ltd, which brings together extensive expertise in the discovery and development of antibodies targeting G protein-coupled receptors (GPCRs) to enable the generation of novel therapeutics for the treatment of autoimmune and inflammatory diseases.
An Option and Research Collaboration Agreement has been established between Monash University and Japan-based Ono Pharmaceutical Co. Ltd, which brings together extensive expertise in the discovery and development of antibodies targeting G protein-coupled receptors (GPCRs) to enable the generation of novel therapeutics for the treatment of autoimmune and inflammatory diseases.
Driver of cystic fibrosis lung inflammation yields target for treatment
Yale researchers have uncovered a driver of the chronic inflammation that damages lungs in cystic fibrosis. It could be a target for treatment. Yale researchers have identified a possible driver of the persistent inflammation that causes irreversible lung damage in patients with cystic fibrosis, a genetic disorder that impairs breathing and digestion.
Yale researchers have uncovered a driver of the chronic inflammation that damages lungs in cystic fibrosis. It could be a target for treatment. Yale researchers have identified a possible driver of the persistent inflammation that causes irreversible lung damage in patients with cystic fibrosis, a genetic disorder that impairs breathing and digestion.
U-M researchers to develop open-access molecular reaction data to speed discovery of drugs
Researchers can invent and test millions of molecules quickly, but to develop successful new drugs, agrochemicals and other futuristic materials, they must first synthesize the molecules-and outcomes are a gamble.
Researchers can invent and test millions of molecules quickly, but to develop successful new drugs, agrochemicals and other futuristic materials, they must first synthesize the molecules-and outcomes are a gamble.
Wearable sensor could guide precision drug dosing
Key takeaways Variations in how different people's bodies react to medicine mean that some antibiotics and anticancer drugs have to be dosed carefully to avoid serious side effects. A new wearable device continuously and painlessly measures the actual amount of medicine taken in by assessing fluid between cells underneath the skin.
Key takeaways Variations in how different people's bodies react to medicine mean that some antibiotics and anticancer drugs have to be dosed carefully to avoid serious side effects. A new wearable device continuously and painlessly measures the actual amount of medicine taken in by assessing fluid between cells underneath the skin.
Large language models help decipher clinical notes
Researchers used a powerful deep-learning model to extract important data from electronic health records that could assist with personalized medicine.
Researchers used a powerful deep-learning model to extract important data from electronic health records that could assist with personalized medicine.
New tools map seizures in the brain, improve epilepsy treatment
Machine learning reveals patterns in brain activity and within minutes can pinpoint where seizures begin Two new models could solve a problem that's long frustrated millions of people with epilepsy and the doctors who treat them: how to find precisely where seizures originate to treat exactly that part of the brain.
Machine learning reveals patterns in brain activity and within minutes can pinpoint where seizures begin Two new models could solve a problem that's long frustrated millions of people with epilepsy and the doctors who treat them: how to find precisely where seizures originate to treat exactly that part of the brain.
New approach could push limits of immunotherapy for difficult-to-treat cancers
Cancerous tumors that aren't candidates for surgery or chemotherapy sometimes respond well to alternatives like immunotherapy, but even cutting-edge cancer treatments that harness the immune system have their limits. A recent study by researchers at the University of Wisconsin-Madison points toward a potential new approach for pushing the limits of immunotherapy, opening a door to more effective treatment of inoperable tumors and metastatic cancer.
Cancerous tumors that aren't candidates for surgery or chemotherapy sometimes respond well to alternatives like immunotherapy, but even cutting-edge cancer treatments that harness the immune system have their limits. A recent study by researchers at the University of Wisconsin-Madison points toward a potential new approach for pushing the limits of immunotherapy, opening a door to more effective treatment of inoperable tumors and metastatic cancer.
Documents highlight role of pharmacies in driving opioid epidemic
The latest documents added to the Opioid Industry Documents Archive illustrate the repeated failure of retail pharmacies to heed warning signs and safety guidelines Johns Hopkins University and the U
The latest documents added to the Opioid Industry Documents Archive illustrate the repeated failure of retail pharmacies to heed warning signs and safety guidelines Johns Hopkins University and the U
Why and when to get a bivalent booster
The newly available COVID-19 boosters offer the best protection against current strains. But who needs a booster and when should they get it?
The newly available COVID-19 boosters offer the best protection against current strains. But who needs a booster and when should they get it?
What you need to know about bivalent boosters for COVID-19
New booster shots designed to target the omicron variant and its subvariants, and the original strain of SARS-CoV-2, could become available in the U.S. in the coming weeks The SARS-CoV
New booster shots designed to target the omicron variant and its subvariants, and the original strain of SARS-CoV-2, could become available in the U.S. in the coming weeks The SARS-CoV
First in Nation: UC San Diego Health Offers Treatment for Hereditary Amyloidosis
New medication allows for less frequent visits for patients, helping improve quality of life UC San Diego Health is first in the nation to offer a new injectable medication to patients with nerve dam
New medication allows for less frequent visits for patients, helping improve quality of life UC San Diego Health is first in the nation to offer a new injectable medication to patients with nerve dam
Documents show McKinsey’s role in fueling opioid crisis
New documents show McKinsey's role in fueling opioid epidemic Consulting firm's work with pharmaceutical companies to help increase sales detailed in UCSF-Johns Hopkins opioid documents archive The O
New documents show McKinsey's role in fueling opioid epidemic Consulting firm's work with pharmaceutical companies to help increase sales detailed in UCSF-Johns Hopkins opioid documents archive The O
Q&A: What you should know about new COVID vaccines for young kids
Vaccines against COVID-19 are finally available for the youngest Americans. The U.S. Food and Drug Administration voted on June 17 to authorize shots from Moderna and Pfizer for children as young as 6 months.
Vaccines against COVID-19 are finally available for the youngest Americans. The U.S. Food and Drug Administration voted on June 17 to authorize shots from Moderna and Pfizer for children as young as 6 months.
UCLA survey quantifies COVID-19 vaccine hesitancy among Californians
Despite the U.S. Food and Drug Administration's full approval of the COVID-19 vaccine, 58.8% of Californians who are not fully vaccinated are still worried about its side effects, according to a new UCLA survey.
Despite the U.S. Food and Drug Administration's full approval of the COVID-19 vaccine, 58.8% of Californians who are not fully vaccinated are still worried about its side effects, according to a new UCLA survey.
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