A study by Yale School of Medicine reveals that survival rates for patients with a thoracic aneurysm are significantly better, and complications are fewer, among patients who take statin cholesterol drugs than those who do not. The study appears in the American Journal of Cardiology.
- Medicine - Oct 31 Is it sorcery or sugar that ails you after Halloween?
- Literature - Oct 31 Symposium to focus on posthumanities Nov. 5-6
- Agronomy - Oct 31 Salt levels in restaurant meals "alarmingly high" - legislation needed, says researcher
- Careers - Oct 31 MIT startups win big at MassChallenge
- Physics - Oct 31 MIT and Tecnológico de Monterrey establish program in nanoscience and nanotechnology
- Business - Oct 31 Statement from Jim Hackett
- Sport Sciences - Oct 31 Remarks by U-M president Mark Schlissel
- Business - Oct 31 U-Michigan President Mark Schlissel appoints interim athletic director
- Chemistry - Oct 31 Nanotubes that Insert Themselves into Cell Membranes
- Microtechnics - Oct 31 $9 million gift from alumnus B. John Garrick launches Institute for the Risk Sciences at UCLA Engineering
- Arts - Oct 31 Artennial celebrates tradition of artistic excellence at UChicago
- Literature - Oct 31 British puppetry theater group Blind Summit teaches master class at Stanford
Statins may protect against death from aneurysm, Yale study finds
An aneurysm is a swelling of an artery, and is a common cause of death. It’s usually asymptomatic, with death or a life-threatening complication such as rupture or dissection being the first manifestation. Statins are cholesterol-lowering drugs that are widely used in patients with cardiovascular disease.
Assistant professor of cardiothoracic surgery Ion S. Jovin, M.D., and colleagues studied 649 patients with thoracic aortic aneurysms: 147 were taking statins and 502 were not. In long-term follow-up 80% of those taking statins survived, compared with 67% percent of those not taking statins. In addition, a smaller percentage of those taking statins suffered a rupture or dissection (splitting of the aorta), compared to those who were not taking statins.
"The intake of statins was associated with an improvement in long-term outcomes among these patients," said co-author John Elefteriades, M.D., professor of cardiothoracic surgery at Yale School of Medicine and director of the Aortic Institute at Yale-New Haven Hospital. "In addition to better survival, fewer patients taking statins required surgical intervention," Elefteriades added.
Medical science has searched for decades for a medicine that could treat aneurysm disease, with little success. The current standard therapy is to keep blood pressure low to discourage rupture of the enlarged artery. Jovin said his research suggests that "statins could offer a significant protective effect to patients at risk of death or complications from aneurysm disease. However, the ultimate proof would be a randomized clinical trial." Elefteriades adds, "We now have some arrows in our quiver of medicines to treat this disease."
Other authors are Mona Duggal, Keita Ebisu, Hyung Paek, A. Dana Oprea, Maryann Tranquilli, John Rizzo, Redin Memet, Marina Feldman, James Dziura, and Cynthia A. Brandt of Yale.
Last job offers
- Mathematics - 31.10
Applied Mathematics- Assistant or Associate Professor (AA8802)
- Chemistry - 31.10
Assistant / Associate/Full Professor-Chemical Engineering
- Arts - 30.10
Assistant Professor - Painting / Drawing
- Mathematics - 30.10
Clinical Assistant / Associate Professor - Mathematics, Statistics, and Computer Science
- Mathematics - 30.10
Clinical Assistant Professor of Math Ed - Mathematics, Statistics, and Computer Science
- Psychology - 30.10
Professeur(e) adjoint(e) en psychologie de l’éducation
- Medicine - 30.10
Assistant / Associate Professor of Environmental Reproductive and Perinatal Epidemiology
- Architecture - 29.10
Associate or Full Professor